Meterpreter Persistence Detected and Removed by Windows Defender and Stopped Working

I created my payload using HERCULES to get the payload through Windows Defender and i succeeded.

but as soon as i created my persistence, the session was closed, I tried to create a new session but the computer on the other side was not listening and the persistence script was deleted.

how do i get the persistence script to get through Windows Defender?

Thanks in advance